This is a prop painting of 'The Madonna Litta' reportedly from episodes of Star Trek: Voyager featuring the holographic character 'Leonardi Da Vinci' (John Rhys Davies) - according to the COA from the It's A Wrap! auction. No screen-caps can be found from those episodes containing this painting.
This painting can be seen as set dressing in the Star Trek: Voyager episode 'The Killing Game' Part 1 in the far left background of the holographic Nazi office (as created by the Hirogen who have taken over the ship and are repeatedly 'hunting' the crew).
The item is a print of the portrait mounted on a wooden back and mounted within a very nice frame. The frame features painted embellishments and a gold colored metal trim around the painting itself. The item measures approx. 22.25 X 25.75 X 1.75 inches and features hand written inscriptions reading ‘STV Da Vinci’ on the reverse and a blue adhesive tape label on the face of the frame reading the same.
A Screen-capis included for reference.
